J Allergy Clin Immunol. 2007 Oct Bisgaard H. PMID: 17637472Read more
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N Engl J Med. 2007 Oct 11 Bisgaard H, Hermansen MN, Buchvald F, Loland L, Halkjaer LB, Bønnelykke K, Brasholt M, Heltberg A, Vissing NH, Thorsen SV, Stage M, Pipper CB. Abstract BACKGROUND: Pathological features of the airway in young children with severe recurrent wheeze suggest an association between bacterial colonization and the initiating eventsRead more
Br J Clin Pharmacol. 2007 Aug Bønnelykke K1, Jespersen JJ, Bisgaard H. Abstract AIMS: To determine the effect of age on systemic exposure to inhaled salbutamol in children. METHODS: Fifty-eight asthmatic children, aged 3-16 years, inhaled 400 microg of salbutamol from a pressurized metered dose inhaler with spacer. The 20 min serum profile was analyzed.Read more
Pediatr Pulmonol. 2007 Aug Bisgaard H, Szefler S. Abstract OBJECTIVE: To determine the prevalence, impact, and treatment of asthma-like symptoms in preschool children in USA and Europe. STUDY DESIGN: 7251 households in USA and Europe with at least one child aged 1-5 years were interviewed by telephone for recurrent days troubled by cough, wheeze orRead more
Respir Med. 2007 Jul Bisgaard H1, Pedersen S, Anhøj J, Agertoft L, Hedlin G, Gulsvik A, Bjermer L, Carlsen KH, Nordvall L, Lundbäck B, Wennergren G, Werner S, Bønnelykke K, Weiss ST. Abstract BACKGROUND: Asthma patients exhibit an increased rate of loss of lung function. Determinants to such decline are largely unknown and the modifyingRead more
Hepatology. 2007 Jun Jelnes P, Santoni-Rugiu E, Rasmussen M, Friis SL, Nielsen JH, Tygstrup N, Bisgaard HC. Abstract The experimental protocols used in the investigation of stem cell-mediated liver regeneration in rodents are characterized by activation of the hepatic stem cell compartment in the canals of Hering followed by transit amplification of oval cells andRead more
Am J Respir Crit Care Med. 2007 Jun 15 Beydon N, Davis SD, Lombardi E, Allen JL, Arets HG, Aurora P, Bisgaard H, Davis GM, Ducharme FM, Eigen H, Gappa M, Gaultier C, Gustafsson PM, Hall GL, Hantos Z, Healy MJ, Jones MH, Klug B, Lødrup Carlsen KC, McKenzie SA, Marchal F, Mayer OH, MerkusRead more
Eur Respir J. 2007 Apr Gammelgaard A, Bisgaard H. Comment on Evidence-based medicines for children: Important implications for new therapies at all ages. [Eur Respir J. 2006] PMID: 17400886Read more
Biomarkers. 2007 Jan-Feb Sørensen M, Bisgaard H, Stage M, Loft S. Abstract Non-invasive biomonitoring of exposure to environmental tobacco smoke (ETS) by means of hair is attractive in children, although systematic evaluation is required in infants. The objective was to compare nicotine and cotinine concentrations in hair and plasma and parentally reported exposure to ETSRead more
Chest. 2006 Dec Bisgaard H1, Le Roux P, Bjåmer D, Dymek A, Vermeulen JH, Hultquist C. Abstract OBJECTIVES: A fixed combination of long-acting beta(2)-agonists (LABA) plus inhaled corticosteroids (ICS) has never been proven to reduce asthma exacerbations vs ICS alone in children. This 12-month, double-blind, randomized study in 341 children (age range, 4 to 11Read more
