J Allergy Clin Immunol. 2002 Aug Asmus MJ, Hendeles L, Weinberger M, Ahrens RC, Bisgaard H, Lötvall J, O’Byrne PM, Cockcroft DW. Comment on Low-dose levalbuterol in children with asthma: safety and efficacy in comparison with placebo and racemic albuterol. [J Allergy Clin Immunol. 2001] PMID: 12170277Read more
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J Allergy Clin Immunol. 2002 Jul Benn CS, Thorsen P, Jensen JS, Kjaer BB, Bisgaard H, Andersen M, Rostgaard K, Björkstén B, Melbye M. Abstract BACKGROUND: Infants with wheezing and allergic diseases have a microflora that differs from that of healthy infants. The fetus acquires microorganisms during birth when exposed to the maternal vaginal microflora.Read more
Eur Respir J. 2002 Jul Baraldi E, de Jongste JC; European Respiratory Society/American Thoracic Society (ERS/ATS) Task Force. Abstract Measurement of fractional exhaled nitric oxide in exhaled air is an exciting innovative technique that gives new insights in to the pathophysiology of lung disease and asthma in particular, with many potential clinical applications. Careful standardisationRead more
Pediatrics. 2002 Mar Anhøj J, Bisgaard AM, Bisgaard H. Abstract OBJECTIVE: To study the systemic activity of inhaled steroids in young children. METHODS: Forty children with mild asthma aged 1 to 3 years were studied in a 3-way crossover, randomized, placebo-controlled, double-blind trial. Treatment with inhaled fluticasone propionate, 200 microg twice daily delivered via pressurizedRead more
Biochem Biophys Res Commun. 2002 Jan 11 Tygstrup N, Bangert K, Ott P, Bisgaard HC. Abstract Liver damage activates processes aimed at repairing damage; simultaneously, liver functions required for survival must be maintained. The expression of genes responsible for both in rat models of lethal (lipopolysaccharide, 90% hepatectomy, and d-galactosamine) and nonlethal (turpentine, 70% hepatectomy,Read more
Chest. 2001 Dec Bisgaard H, Price MJ, Maden C, Olsen NA. Abstract STUDY OBJECTIVES: To evaluate the cost-effectiveness of inhaled fluticasone propionate (FP) in children aged 12 to 47 months with asthma symptoms. DESIGN: A retrospective economic analysis conducted from the perspective of the Danish health-care system, based on clinical data from a 12-week study.Read more
Ugeskr Laeger. 2001 Nov 12 [Article in Danish] Bisgaard H1, Pedersen SE, Schiøtz PO. Abstract Paediatric pulmonology (paediatric respiratory medicine) concerns such lung diseases in children as asthma, pneumonia, cystic fibrosis, primary ciliary dyskinesia, chronic interstitial pneumonia, bronchopulmonary dysplasia and congenital abnormalities. This specialty has been approved as an official subsection of the European ConfederationRead more
J Allergy Clin Immunol. 2001 Oct Roorda RJ, Mezei G, Bisgaard H, Maden C. Abstract BACKGROUND: Many uncertainties remain in the diagnosis and treatment of preschool children with asthma symptoms. OBJECTIVE: We sought to determine the subgroups of preschool children (aged 12-47 months) with recurrent asthma symptoms most likely to respond to inhaled fluticasone propionateRead more
Pediatrics. 2001 Sep Knorr B, Franchi LM, Bisgaard H, Vermeulen JH, LeSouef P, Santanello N, Michele TM, Reiss TF, Nguyen HH, Bratton DL. Abstract BACKGROUND: The greatest prevalence of asthma is in preschool children; however, the clinical utility of asthma therapy for this age group is limited by a narrow therapeutic index, long-term tolerability, andRead more
Am J Respir Crit Care Med. 2001 Aug 15 Nielsen KG1, Bisgaard H. Abstract The primary aim of this study was to quantify and compare bronchodilator responsiveness in healthy and asthmatic children aged 2 to 5 yr. The secondary aim of the study was to compare discriminative capacity (i.e., sensitivity, specificity, and predictive values ofRead more
